Cho-Arg (trifluoroacetate salt) T36350

Product Introduction
Bioactivity


英文名: Cho-Arg (trifluoroacetate salt)

描述: Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and the caveolae-mediated endocytosis inhibitor genistein . It is cytotoxic to H1299 cells (IC50 = 88.5 μg/ml).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMF : 50 mg/mL
DMSO : 50 mg/mL
Ethanol : 50 mg/mL
Ethanol:PBS (pH 7.2) (1:3) : 0.25 mg/mL


关键字: Cho Arg (trifluoroacetate salt) | ChoArg (trifluoroacetate salt) | Cho-Arg

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途