化合物 PRLX-93936 hcl T36404L
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 1094210-96-4 | ¥6,880.00 | 询底价 |
10 mg | 1094210-96-4 | ¥4,320.00 | 询底价 |
100 mg | 1094210-96-4 | ¥12,500.00 | 询底价 |
1 mg | 1094210-96-4 | ¥1,300.00 | 询底价 |
500 mg | 1094210-96-4 | ¥25,200.00 | 询底价 |
50 mg | 1094210-96-4 | ¥9,330.00 | 询底价 |
5 mg | 1094210-96-4 | ¥2,920.00 | 询底价 |
Product Introduction
Bioactivity
英文名: PRLX-93936 HCL
描述: PRLX-93936 HCL 是 erastin 的类似物,并显示出与顺铂对非小细胞肺癌 (NSCLC) 细胞的协同作用。
体外活性: Cotreatment with cisplatin and PRLX93936 induced ferroptosis, as evidenced by the upregulation of ROS, lipid peroxidation and Fe2+. Further investigation revealed that cotreatment with cisplatin and PRLX93936 inhibited GPX4 and that overexpression of GPX4 prevented cell death. Moreover, the Nrf2/Keap1 pathway also regulated the sensitivity to cisplatin and PRLX93936 in NSCLC cells. Nrf2 silencing increased this sensitivity while inhibition of Keap1 attenuated it[1].
存储条件: keep away from moisture,store under nitrogenPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50.00mg/ml
关键字: PRLX93936 HCL | PRLX 93936 HCL | PRLX-93936 HCL
相关产品: NADPH tetrasodium salt | Ferroptosis-IN-3 | Deferasirox | Bardoxolone Methyl | Dopamine hydrochloride | L-Glutamic acid monosodium salt | Anticancer agent 147 | Artemisinin | FINO2 | Lapatinib Ditosylate
相关库: Drug Repurposing Compound Library | Anti-Prostate Cancer Compound Library | Anti-Breast Cancer Compound Library | Mitochondria-Targeted Compound Library | Anti-Cancer Drug Library | NF-κB Signaling Compound Library | Bioactive Compounds Library Max | Anti-Lung Cancer Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Active Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途