(3S)-hydroxy Quinidine T36561

Product Introduction
Bioactivity


英文名: (3S)-hydroxy Quinidine

描述: (3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Methanol : Soluble


关键字: (3S) hydroxy Quinidine | (3S)hydroxy Quinidine | hydroxy Quinidine

(3S)-hydroxy Quinidine T36561信息由TargetMol中国为您提供，如您想了解更多关于(3S)-hydroxy Quinidine T36561报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途