化合物T36579 T36579

Product Introduction
Bioactivity


英文名: GLP-1R Agonist DMB

描述: GLP-1R Agonist DMB 是胰高血糖素样肽1受体的激动剂（GLP-1R；重组人受体的 KB＝26.3nM）。

体外活性: GLP-1R Agonist DMB inhibits forskolin-induced cAMP accumulation in BHK cells expressing the recombinant human receptor with an EC50 value of 101 nM. GLP-1R Agonist DMB (100 and 1,000 nM) increases insulin levels induced by D-(+)-glucose in pancreatic islets isolated from wild-type, but not Glp1r knockout, mice[1].

体内活性: GLP-1R Agonist DMB reduces fasting plasma glucose levels in mice when administered at a dose of 5 μmol/kg[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 9mg/mL (25.8mM)


关键字: GLP1R Agonist DMB | GLP 1R Agonist DMB | GLP-1R Agonist DMB

相关产品: Teduglutide | V-0219 hydrochloride | (S, R)-LSN 3318839 | 3-Deoxyglucosone | GLP-1 receptor agonist 9 | Semaglutide TFA (910463-68-2 free base) | GLP-1R Antagonist 1 | Survodutide | Tirzepatide sodium salt | GRA Ex-25

相关库: Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Obesity Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途