DL-Sulforaphane N-acetyl-L-cysteine T36614
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 334829-66-2 | ¥3,370.00 | 询底价 |
10 mg | 334829-66-2 | ¥5,960.00 | 询底价 |
1 mg | 334829-66-2 | ¥770.00 | 询底价 |
Product Introduction
Bioactivity
英文名: DL-Sulforaphane N-acetyl-L-cysteine
描述: Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress. Unless activated by inflammatory, environmental, or oxidative stressors, Nrf2 is sequestered in the cytoplasm by its repressor, Keap1. Because of its protective capabilities, small molecules that activate Nrf2 signaling are being examined as potential anti-cancer or anti-inflammatory agents. DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is a major metabolite of SFN , a powerful inducer of chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression. At 75 μM, SFN-NAC has been shown to increase ARE expression in HepG2-C8 cells. Its reported potency on ARE-related gene expression is roughly 8-fold less than SFN.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 10 mg/mL
PBS (pH 7.2) : 10 mg/mL
Ethanol : 5 mg/mL
DMF : 10 mg/mL
关键字: DL Sulforaphane N acetyl L cysteine | DLSulforaphane NacetylLcysteine | DL-Sulforaphane N-acetyl-L-cysteine
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途