莪术醇 T3669

Product Introduction
Bioactivity


英文名: Curcumenol

描述: Curcumenol ((+)-Curcumenol) 提取具有药用价值的 Curcuma zedoaria，是高效的 CYP3A4抑制剂(IC50=12.6 μM)，具有神经抗肿瘤、保护、抗炎、和保肝的作用。它在 LPS 刺激的 BV-2 小胶质细胞中，抑制 Akt 介导的 NF-κB 活化及 p38 MAPK 信号通路。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 18.33 mg/mL (78.25 mM)


关键字: CYPs | Cytochrome P450 | Inhibitor | inhibit | Curcumenol

相关产品: Ranitidine | Bucolome | 2-Hydroxy-1-Methoxyaporphine | Eupatorin | Avasimibe | EN3356 | Miltirone | Antihistamine-1 | Chrysosplenetin | 15-Hydroxydehydroabietic acid

相关库: Oxidation-Reduction Compound Library | Selected Plant-Sourced Compound Library | Chinese Pharmacopoeia Natural Product Library | Inhibitor Library | Human Endogenous Metabolite Compound Library Plus | Anti-Cancer Active Compound Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途