CAY10760 T36703

Product Introduction
Bioactivity


英文名: CAY10760

描述: CAY10760 is an inhibitor of the protein-protein interaction between RAD51 recombinase and BRCA2 (EC50= 19 μM in a cell-free competitive ELISA).1It decreases homologous recombination by 54% in wild-typeBRCA2-expressing BxPC-3 pancreatic cancer cells when used at a concentration of 20 μM. CAY10760 (20 μM) decreases proliferation of BxPC-3, as well as mutantBRCA2-expressing Capan-1, cancer cells when used alone or in combination with the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib .

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMF : 11 mg/mL
DMF:PBS (pH 7.2) (1:2) : 0.3 mg/mL
DMSO : 10 mg/mL


关键字: CAY10760 | CAY 10760 | CAY-10760

CAY10760 T36703信息由TargetMol中国为您提供，如您想了解更多关于CAY10760 T36703报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途