1-Octadecyl Lysophosphatidic Acid T36768

Product Introduction
Bioactivity


英文名: 1-Octadecyl Lysophosphatidic Acid

描述: 1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 10 mg/mL
Ethanol : 10 mg/mL
Ethanol:PBS (pH 7.2) ((1:1) : 0.5 mg/mL
DMF : 10 mg/mL


关键字: 1 Octadecyl Lysophosphatidic Acid | 1Octadecyl Lysophosphatidic Acid | 1-Octadecyl Lysophosphatidic Acid

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