Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate) T36807
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | 价格 | 操作 |
---|---|---|
25 mg | ¥4,420.00 | 询底价 |
50 mg | ¥6,930.00 | 询底价 |
5 mg | ¥1,270.00 | 询底价 |
10 mg | ¥2,410.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)
描述: Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 substrates, including the non-cholestatic estrogen metabolite, estradiol 3-(β-D-glucuronide) .2,3E217G has also been reported to be transported by MDR1, MRP1, MRP3, MRP4, MRP7, ABCG2 (a breast cancer resistance protein transporter), and the rat organic anion-transporting polypeptides 1-4.2
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO:PBS (pH 7.2) (1:1) : 0.5 mg/mL
DMF : 10 mg/mL
DMSO : 20 mg/mL
关键字: Estradiol 17-(β-D-Glucuronide) | Estradiol 17-(b-D-Glucuronide) | Estradiol 17-(beta-D-Glucuronide) | sodium Hydrate | Estradiol 17 (β D Glucuronide) (sodium salt hydrate) | Estradiol 17(βDGlucuronide) (sodium salt hydrate)
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途