L-烯丙基甘氨酸 T37190

Product Introduction
Bioactivity


英文名: L-Allylglycine

描述: L-Allylglycine 是 GABA 合成酶（谷氨酸脱羧酶）的有效抑制剂。

体外活性: L-allylglycine inhibits glutamic acid decarboxylase(GAD) only when used at high concentrations (1-80 mM). The more potent in vivo activity can be attributed to metabolic conversion of L-allylglycine to 2-keto-4-pentanoic acid, a more potent convulsant and GAD inhibitor[1].

体内活性: The stereoisomers of allylglycine were injected into the posterior hypothalamus at a site also shown to be reactive to bicuculline. Injection of L-allylglycine but not D-allylglycine caused substantial increases in heart rate but only slight increases in blood pressure[1].

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: PBS (pH 7.2) : 10 mg/mL
Ethanol : Insoluble


关键字: Inhibitor | LAllylglycine | L-Allylglycine | L Allylglycine | inhibit

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