14,15-dehydro Leukotriene B4 T37260
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 μg | 114616-11-4 | ¥8,590.00 | 询底价 |
25 μg | 114616-11-4 | ¥2,410.00 | 询底价 |
50 μg | 114616-11-4 | ¥4,560.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 14,15-dehydro Leukotriene B4
描述: Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM. 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 μM.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: PBS (pH 7.2) : >1 mg/mL
DMF : Miscible
DMSO : Miscible
Ethanol : Miscible
关键字: 14,15 dehydro Leukotriene B4 | 14,15-dehydro Leukotriene B-4 | 14,15dehydro Leukotriene B4
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途