6-O-desmethyl Donepezil T37360

Product Introduction
Bioactivity


英文名: 6-O-desmethyl Donepezil

描述: 6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil . It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6. It inhibits human ether a go-go (hERG) channels (IC50 = 1.5 μM in HEK293 cells expressing hERG).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Chloroform : Soluble
Methanol : Soluble


关键字: 6-O-desmethyl Donepezil | 6Odesmethyl Donepezil | 6 O desmethyl Donepezil

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途