6β-hydroxy Dexamethasone T37361

Product Introduction
Bioactivity


英文名: 6β-hydroxy Dexamethasone

描述: 6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans., The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Methanol : Slightly soluble


关键字: 6β-hydroxy Dexamethasone | 6β hydroxy Dexamethasone | 6βhydroxy Dexamethasone | 6beta-hydroxy Dexamethasone | 6b-hydroxy Dexamethasone

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途