C18 Phytoceramide (t18:0/18:0) T37458

Product Introduction
Bioactivity


英文名: C18 Phytoceramide (t18:0/18:0)

描述: C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer(t18:0/18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. It also inhibits expression of the allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated murine skin tissue. Formulations containing cer(t18:0/18:0) have been used used in cosmetics as a skin protectants as they reduce water loss to prevent epidermal dehydration and irritation.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Chloroform:Methanol (1:1) : Soluble


关键字: C18 Phytoceramide | C-18 Phytoceramide (t18:0/18:0) | C18 Phytoceramide (t18:0/18:0) | t18:0/18:0

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途