Leukotriene B4 Ethanolamide T37619
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 μg | 877459-63-7 | ¥4,580.00 | 询底价 |
25 μg | 877459-63-7 | ¥2,620.00 | 询底价 |
100 μg | 877459-63-7 | ¥8,620.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Leukotriene B4 Ethanolamide
描述: The effects of Leukotriene B4 (LTB4) are mediated by two known receptors, BLT1 and BLT2. LTB4 is a high affinity ligand for BLT1, and many of its pro-inflammatory effects are believed to be transduced through this receptor. The BLT2 is more enigmatic, in that LTB4 is not a high-affinity ligand, nor is it clear that BLT2 activation promotes inflammation. LTB4 ethanolamide (LTB4-EA) is a theoretical 5-LO metabolite of arachidonoyl ethanolamide (AEA). In CHO cells transfected with human BLTR1, LTB4-EA was a potent antagonist with about three times greater affinity for the receptor than LTB4 (Ki = 1.22 nM versus 3.88 nM). LTB4-EA antagonizes the LTB4-induced contractions of guinea pig lung parenchyma with an EC50 of 10 nM. LTB4-EA thus represents a potential endogenous anti-inflammatory compound functioning as a natural antagonist of BLTR1.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMF : 100 mg/mL
PBS (pH 7.2) : 12 mg/mL
DMSO : 100 mg/mL
Ethanol : 100 mg/mL
关键字: Leukotriene B-4 Ethanolamide | Leukotriene B4 Ethanolamide
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途