17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid T37633

Product Introduction
Bioactivity


英文名: 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid

描述: 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 20 mg/mL
DMSO : 10 mg/mL
DMF : 15 mg/mL


关键字: 17oxo4(Z),7(Z),10(Z),13(Z),15(E),19(Z)Docosahexaenoic Acid | 17-oxo-4,7,10,13,15,19Docosahexaenoic Acid | 17 oxo 4(Z),7(Z),10(Z),13(Z),15(E),19(Z) Docosahexaenoic Acid

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途