辛酰基-L-高丝氨酸内酯 T37744

Product Introduction
Bioactivity


英文名: N-octanoyl-L-Homoserine lactone

描述: N-octanoyl-L-Homoserine lactone (C8-HSL) 是一种具有扩散性的外源性鼠疫耶尔森菌群体感应分子，可调节LcrV毒力因子，通过参与群体感应控制基因表达，影响细胞代谢。N-octanoyl-L-Homoserine lactone 是用于研究囊性纤维的感染。

体外活性: Nitric oxide radical (NO) release was significantly higher when C8-HSL MPs were combined with particulate vaccines for measles and Zika. C8-HSL MPs showed immunostimulatory potential when combined with the influenza vaccine. The results showed that C8-HSL MPs were as immunogenic as FDA-approved adjuvants such as alum, MF59, and CpG. This proof-of-concept study showed that C8-HSL MP displayed adjuvant potential when combined with several particulate vaccines, indicating that C8-HSL MPs can increase the immunogenicity of both bacterial and viral vaccines.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 60 mg/mL (263.97 mM)
DMF : 20 mg/mL


相关产品: Fusidic acid sodium salt | 6-Diazo-5-oxo-L-nor-Leucine | Qstatin | BTZ043 Racemate | Dup-721 | Pymetrozine | Nithiamide | (-)-Epigallocatechin-3-(3''-O-methyl) gallate | Lomefloxacin hydrochloride | Povidone iodine

相关库: Bioactive Compounds Library Max | Covalent Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途