Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) T37851

Product Introduction
Bioactivity


英文名: Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)

描述: Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) is an inducer of ferroptosis.1 It induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells when used at a concentration of 3 μM.1 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) inhibits proliferation of BJAB, NALM-6, Jurkat, MelHO, and MCF-7 cancer cells (IC50s = 0.07, 2.5, 1.5, 3, and 5 μM, respectively), as well as NALM-6 cells resistant to daunorubicin and vincristine when used at concentrations ranging from 0.04 to 0.125 μM.2

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 14 mg/mL
DMF : 20 mg/mL
PBS (pH 7.2) : Partially Soluble
Ethanol : 0.3 mg/mL


关键字: Chlorido[N,N'disalicylidene1,2phenylenediamine]iron(III) | Chlorido[N,N' disalicylidene 1,2 phenylenediamine]iron(III)

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途