17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide T37941

Product Introduction
Bioactivity


英文名: 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

描述: Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMF : 25 mg/mL
PBS (pH 7.2) : 0.25 mg/mL
Ethanol : 50 mg/mL
DMSO : 25 mg/mL
Acetonitrile : 3 mg/mL


关键字: 17phenyl trinor Prostaglandin F2α cyclopropyl methyl amide | 17-phenyl trinor Prostaglandin F-2α cyclopropyl methyl amide | 17 phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途