17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α T37948

Product Introduction
Bioactivity


英文名: 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α

描述: A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.417-trifluoromethylphenyl-13,14-dihydro trinor PGF2αbears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2αwould act very much like the free acid of latanoprost.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMF : 30 mg/mL
Ethanol : 50 mg/mL
PBS (pH 7.2) : 1 mg/mL
DMSO : 25 mg/mL


关键字: 17trifluoromethylphenyl13,14dihydro trinor Prostaglandin F2α | 17 trifluoromethylphenyl 13,14 dihydro trinor Prostaglandin F2α | 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F-2α

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