β-Endorphin (1-27) (human) (trifluoroacetate salt) T38193
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | 价格 | 操作 |
---|---|---|
1 mg | ¥4,230.00 | 询底价 |
Product Introduction
Bioactivity
英文名: β-Endorphin (1-27) (human) (trifluoroacetate salt)
描述: β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). It binds to rat and mouse brain membrane preparations (IC50s = 1.1 and 5.7 nM, respectively) and induces chemotaxis of human monocytes in vitro when used at a concentration of 1 nM. Intracerebroventricular administration of β-endorphin (1-27) increases the latency to tail withdrawal in response to thermal stimulation in mice with a median antinociceptive dose (AD50) of 1,500 pmol per animal. It inhibits antinociception induced by β-endorphin in mice in response to thermal stimuli when administered at a dose of 65 pmol per animal. In rats, β-endorphin (1-27) does not affect drug-associated place preference when administered at doses up to 20 μg, i.c.v., but inhibits β-endorphin-induced place preference when administered at a dose of 10 μg per animal.
存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 1 mg/mL
关键字: β-Endorphin | b-Endorphin | β Endorphin (1 27) (human) (trifluoroacetate salt) | βEndorphin (127) (human) (trifluoroacetate salt) | beta-Endorphin
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