1-β-D-Glucosylsphingadienine (d18:2 (4E,8E)) T38213
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 114200-59-8 | ¥1,980.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))
描述: 1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher's disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3); thus, glucosylsphingosine has been used as a key biomarker of the disease. This product contains 1-β-D-glucosylsphingadienine isolated from plants.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Chloroform:Methanol (4:1) : Soluble
关键字: 1 β D Glucosylsphingadienine (d18:2 (4E,8E)) | 1-β-D-Glucosylsphingadienine (d-18:2 (4E,8E)) | 1-beta-D-Glucosylsphingadienine (d18:2 ) | 1βDGlucosylsphingadienine (d18:2 (4E,8E)) | 1-b-D-Glucosylsphingadienine (d18:2 ) | 1-β-D-Glucosylsphingadienine (d18:2 )
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途