Thalidomide-5-CH2-NH2 hydrochloride T38408
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 1010100-22-7 | ¥2,453.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Thalidomide-5-CH2-NH2 hydrochloride
描述: Thalidomide-5-CH2-NH2 (hydrochloride) is a derivative of Thalidomide that serves as a cereblon ligand, specifically utilized for the recruitment of CRBN protein. This compound, Thalidomide-5-CH2-NH2 (hydrochloride), can be connected to a protein ligand through a linker, resulting in the formation of PROTACs.
体外活性: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Thalidomide-5-CH2-NH2 Hydrochloride | Thalidomide 5 CH2 NH2 hydrochloride | Thalidomide5CH2NH2 hydrochloride | Thalidomide-5-CH-2-NH2 hydrochloride
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途