NSC 80467 T38414
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 101982-51-8 | ¥834.00 | 询底价 |
5 mg | 101982-51-8 | ¥1,390.00 | 询底价 |
10 mg | 101982-51-8 | ¥2,760.00 | 询底价 |
Product Introduction
Bioactivity
英文名: NSC 80467
描述: NSC 80467, a selective DNA damaging agent, functions by inhibiting survivin. Specifically, it preferentially targets DNA synthesis, leading to the induction of two distinct markers of DNA damage, namely γH2AX and pKAP1.
体外活性: NSC 80467 has a similar spectrum of activity against the NCI-60 cell line panel, suppresses survivin expression, shows COMPARE correlation with DNA damaging agents, preferentially inhibits DNA synthesis, and induces a DNA damage response characterized by enhanced γH2AX and pKAP1 at concentrations lower than those capable of inhibiting survivin expression[1]. NSC 80467 (200 or 800 nM; 24 hours) inhibits surviving[1]. Western Blot Analysis[1]Cell Line: PC3 cells Concentration: 200 or 800 nM Incubation Time: 24 hours Result: Associated with inhibition of survivin expression.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: NSC 80467 | NSC-80467 | NSC80467
NSC 80467 T38414信息由TargetMol中国为您提供,如您想了解更多关于NSC 80467 T38414报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途