D,L-erythro-PDMP T38489

Product Introduction
Bioactivity


英文名: D,L-erythro-PDMP

描述: D,L-erythro-PDMP, an erythro isomer of PDMP, exhibits growth inhibition on cultured rabbit skin fibroblasts. Additionally, this compound serves as an effective inhibitor of UDP-glucose: ceramide glucosyltransferase.

体外活性: D,L-erythro-PDMP (0, 12, 25, 50 μM; 0, 4, 7, 10 days) shows an inhibitory effect on cell growth of rabbit skin fibroblasts[1]. D,L-erythro PDMP (50 μM; 3 days) has cytotoxic of rabbit skin fibroblasts on cell morphology[1]. D,L-erythro-PDMP (40 μM; 24 h; MDCK cells) induces a marked increase in glucosyltransferase specific activity: 14.6 nmol/h per mg protein[2]. D,L-erythro-PDMP (40 μM; 6 h) protects the cells against loss of synthase in cells exposed to cycloheximide[2]. Cell Proliferation Assay[1]Cell Line: Rabbit skin fibroblast Concentration: 0, 12, 25, 50 μM Incubation Time: 0, 4, 7, 10 days Result: Showed an inhibitory effect on cell growth. Cell Cytotoxicity Assay[1]Cell Line: Rabbit skin fibroblast Concentration: 50 μM Incubation Time: 3 days Result: Had cytotoxic on cell morphology.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: D,L-erythro-PDMP | D,LerythroPDMP | D,L erythro PDMP

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途