(2-pyridyldithio)-PEG1-hydrazine T38503

Product Introduction
Bioactivity


英文名: (2-pyridyldithio)-PEG1-hydrazine

描述: (2-Pyridyldithio)-PEG1-hydrazine is a one-unit cleavable polyethylene glycol (PEG) linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This linker offers the advantage of controlled release of the drug payload from the ADC construct. It is utilized in the conjugation process between the antibody and the cytotoxic drug, enabling the targeted delivery of the drug to cancer cells. The (2-pyridyldithio) group of this linker provides stability during circulation in the bloodstream, while the hydrazine moiety allows for efficient drug release at the tumor site. Overall, the (2-pyridyldithio)-PEG1-hydrazine linker serves as a valuable tool in the development of targeted chemotherapeutic agents for cancer treatment.

体外活性: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: (2pyridyldithio)PEG1hydrazine | (2 pyridyldithio) PEG1 hydrazine | (2-pyridyldithio)-PEG-1-hydrazine

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途