Pirepemat T38610

Product Introduction
Bioactivity


英文名: Pirepemat

描述: Pirepemat (IRL752) is a cortical-preferring catecholamine agent that enhances cognition. It is utilized in the investigation of Parkinson's disease.

体外活性: IRL752 displayed its highest in vitro affinities for 5-HT and NA-related targets[2].

体内活性: IRL752 (3.7-100 μmol/kg, s.c.) has no significant effect on acute hyper-dopaminergic or hypo-glutamatergic motor responses, but reversed deficits resulting from hypomonoaminergic function[2]. Animal Model: Normal rats[2]. Dosage: 3.7-100 μmol/kg. Administration: s.c., 30 min prior to testing. Result: Induced dose-dependent and regio-selective alterations in brain monoamine transmission indices and gene expression.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: IRL-752 | Pirepemat | IRL 752

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途