BIM-23190 T39262

Product Introduction
Bioactivity


英文名: BIM-23190

描述: BIM-23190 is a somatostatin analog that acts as a selective agonist for SSTR2 and SSTR5 receptors. It displays potency with K i values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 finds utility in cancer and acromegaly research.

体外活性: BIM-23190 tends to mildly stimulate PRL secretion[1].

体内活性: BIM-23190 (50 μg/mouse, twice a day) exhibits significant anti-tumor (C6 glioma) activity[2]. Animal Model: Male athymic nude (nu/nu) mice, 5-6 wk old (C6 glioma)[2]. Dosage: 50 μg/mouse Administration: Injected twice a day for 19 days. Result: Significantly reduced the tumor growth rate.

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: BIM-23190 | BIM 23190 | BIM23190

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途