非诺贝特胆碱 T3941

Product Introduction
Bioactivity


英文名: Choline Fenofibrate

描述: Choline Fenofibrate (Trilipix) 是 Fenofibric acid 的胆碱盐，在胃肠道中释放游离的 Fenofibric acid。Fenofibric acid 是一种合成的苯氧基异丁酸衍生物和具有抗高血脂活性的前药。

激酶实验: Cells are harvested, washed, and lysed in NP-40 lysis buffer (50 mM Tris-HCl [pH 7.5], 150 mM NaCl, 0.5% NP-40). Total cell protein is quantified using the Bradford assay and 1-mg/mL protein aliquots are made. Ten microliters of total cell protein is mixed with 290 μL of substrate solution (0.1 mg/mL dithiothreitol [DTT], 0.1 mg/mL albumin, and 1 mM alanine-β-naphthylamide). Fluorometric measurements (340 nm excitation, 400 nm emission) are made after 15 and 30 min. The slope of the line between the 15- and 30-min measurements is used to represent aminopeptidase activity. Total cell protein is preincubated with bestatin, amastatin, puromycin, EDTA, and/or ZnCl2 for 20 min before the fluorometric aminopeptidase assay.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 6.2 mg/mL


关键字: hyperlipidemia | Cyclooxygenase | Fenofibric | ABT335 | hypolipidemic | anti-inflammatory | COX | Inhibitor | PPAR | ABT 335 | acid | Choline Fenofibrate | Peroxisome proliferator-activated receptors | inhibit

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途