HKPerox-2 T39754

Product Introduction
Bioactivity


英文名: HKPerox-2

描述: HKPerox-2 is an excellently selective and sensitive green fluorescent probe toward H 2 O 2 over 30-fold other tested ROS/RNS in chemical and biological systems. HKPerox-2 is a O-methyl rhodol derivative and specifically recognize H 2 O 2 based on a tandem payne/dakin reaction.

体外活性: HKPerox-2 is a O-methyl rhodol derivative and reaches a plateau within 30 min upon treatment of 100 μM H 2 O 2 , and the rate constants k obs is determined to be 2.0x10 -2 s for HKPerox2[1].HKPerox-2 (0-20 μM; 24 hours) is nontoxic to cells at working concentrations in RAW264.7 macrophages[1].HKPerox-2 should be co-incubated with 100 μM of trichloroacetonitrile (CCl3CN, HY-Y0789) for H 2 O 2 detection and molecular imaging. DMSO should be avoided during H 2 O 2 detection, as DMSO could scavenge activated H 2 O 2 in the presence of CCl3CN . DMF is the recommended solvent to prepare probe stock solution.

存储条件: keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: HKPerox 2 | HKPerox-2 | HKPerox2

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途