PDE12-IN-1 T39796

Product Introduction
Bioactivity


英文名: PDE12-IN-1

描述: PDE12-IN-1 is a powerful and specific inhibitor of PDE12, exhibiting a pIC 50 value of 9.1 for enzyme inhibition. It effectively enhances levels of 2′,5′-linked adenylate polymers (2-5A), with a pEC 50 value of 7.7. Additionally, PDE12-IN-1 demonstrates antiviral activity.

体外活性: PDE12-IN-1 inhibits the EMCV-induced cytopathic effect in HeLa Ohio cells with a pIC 50 of 6.7. PDE12-IN-1 inhibits HeLa Ohio cell proliferation in the absence of EMCV infection with a pIC 50 of 5.7. PDE12-IN-1 inhibits the proliferation of both HeLa and HeLaΔPDE12 cells with a pIC 50 of 5.7. PDE12-IN-1 inhibits HRV infection with a pIC50 of 6.9[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: PDE-12-IN-1 | PDE12 IN 1 | PDE12IN1

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途