CGP78850 T40219

Product Introduction
Bioactivity


英文名: CGP78850

描述: CGP78850 is a potent and selective Grb2 SH2-phosphopeptide interaction antagonist that holds potential for cancer research.

体外活性: CGP78850 (0~100 μM; 90 minutes; MDA-MB-468 cells) reduces the amount of associated Grb2 protein in a dose-dependent manner[1]. CGP78850 blocks epidermal growth factor receptor (EGFR)-Grb2 and Shc-Grb2 interaction in living cells. CGP78850 inhibits MDA-MB-468 cells to form colonies in soft agar in a dose-dependent manner[1]. Western Blot Analysis[1]Cell Line: MDA-MB-468 cells Concentration: 0~100 μM Incubation Time: 90 minutes Result: Reduced the amount of associated Grb2 protein in a dose-dependent manner.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: CGP-78850 | CGP 78850 | CGP78850

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途