AV-153 T40345
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 27296-05-5 | ¥10,600.00 | 询底价 |
Product Introduction
Bioactivity
英文名: AV-153
描述: AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand breaks, resulting in reduced DNA damage and stimulation of DNA repair in human cells in vitro. AV-153 also interacts with thymine and cytosine and influences poly(ADP)ribosylation. Moreover, AV-153 exhibits anti-cancer activity.
体外活性: AV-153 causes IC 50 s for Raji and HL-60 cells of 14.9 mM and 10.3 mM, respectively[1]. AV-153 (1 nM to 10 μM; 3 hours) reduces the level of spontaneously arising DNA single-strand breaks (SSBs) in peripheral blood lymphocytes or HL-60 cells by 13-67%[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: AV-153 | AV 153 | AV153
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途