Ensitrelvir fumarate T40358
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 2757470-18-9 | ¥993.00 | 询底价 |
2 mg | 2757470-18-9 | ¥589.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Ensitrelvir fumarate
描述: Ensitrelvir (S-217622) fumarate is a novel orally active inhibitor, targeting the SARS-CoV-2 3CL protease (IC50 = 13 nM). It demonstrates non-covalent and non-peptidic characteristics. This compound represents a pioneering advancement in the development of effective antiviral agents against the SARS-CoV-2 virus.
体外活性: In a cytopathic effect (cpe)-inhibition assay of SARS-CoV-2 infected VeroE6/TMPRSS2 cells, Ensitrelvir fumarate shows the EC 50 values are approximately 0.4 μM for both wild-type virus and Alpha, Beta, Gamma and Delta variants. EC 50 values for SARS-CoV and MERS-CoV were 0.21 and 1.4 μM respectively[1].
体内活性: Ensitrelvir fumarate dose-dependently inhibits intrapulmonary replication of SARS-CoV-2 in mice[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Ensitrelvir Fumarate | Ensitrelvir fumarate | S 217622 Fumarate | S217622 Fumarate | S-217622 Fumarate
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途