头孢比普酯 T40475

Product Introduction
Bioactivity


英文名: Ceftobiprole medocaril

描述: Ceftobiprole medocaril (BAL5788) 是 Ceftobiprole 的前药。Ceftobiprole 是一种广谱的头孢菌素，对耐甲氧西林金黄色葡萄球菌具有活性。

体内活性: Ceftobiprole medocaril (10, 40, 160 mg/kg; single dose; sc) has T 1/2 s from 20 min to 31 min, as the dose rose from 40 mg/kg to 160 mg/kg. The AUC/dose values for the escalating single doses ranges from 0.585 to 1.33, and the C max /dose values decreases from 1.08 to 0.90 in neutropenic thigh-infected mice [1]. The drug showed activities in the lung model similar to those in the thigh model.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Ceftobiprole medocaril | Inhibitor | BAL 5788 | penicillin | cephalosporin | inhibit | gram-positive | pyrrolidinone | MRSA | Bacterial | vancomycin | pathogens | staphylococci | BAL-5788 | gram-negative | VRSA | methicillin | Prodrug

相关产品: Colistin sulfate | β-Glucuronidase-IN-1 | Davercin | Acetylspiramycin | Cetylpyridinium Chloride | Myristoyl glutamic acid | Lactobionic acid | piperacillin | Beta-mangostin | Poly-L-lysine hydrochloride

相关库: FDA-Approved & Pharmacopeia Drug Library | Pediatric Drug Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途