N,N-二甲基硫脲 T40615
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 534-13-4 | ¥387.00 | 询底价 |
500 mg | 534-13-4 | ¥417.00 | 询底价 |
Product Introduction
Bioactivity
英文名: N,N'-Dimethylthiourea
描述: N,N'-Dimethylthiourea (DMTU) 是一种分离自黑蒜的化合物。N,N'-Dimethylthiourea 具有口服活性的羟基自由基 (•OH) 的清除剂,通过活化的中性粒细胞在体外阻止 •OH 的产生。N,N'-Dimethylthiourea 通过发挥 •OH 清除和抗炎作用,防止水浸限制应激诱导的大鼠胃粘膜损伤。
体内活性: N,N'-Dimethylthiourea (DMTU; 1, 2.5, or 5 mmol/kg; orally) administered at 0.5 h before the onset of WIRS reduces the severity of gastric mucosal lesions with attenuation of the changes in the levels of gastric mucosal MPO, pro-inflammatory cytokines, LPO, NOx, nonprotein SH, and vitamin C and gastric adherent mucus found at 3 h after the onset of WIRS in a dose-dependent manner in Male Wistar rats aged 6 weeks [1]. DMTU protects against WIRS-induced gastric mucosal lesions in rats by exerting its antioxidant action including ·OH scavenging and its anti-inflammatory action without affecting the stress response.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (479.98 mM)
关键字: N,N'-Dimethylthiourea | Inhibitor | N,N' Dimethylthiourea | inhibit | WIRS | scavengin | N,N'Dimethylthiourea | orally
相关产品: Succinobucol | Astragaloside III | Tyrosol | DL-Syringaresinol | Nordihydroguaiaretic acid | 8-Hydroxyapigenin | Kaempferol 3-sophoroside-7-glucoside | (-)-Anonaine | Isochlorogenic acid C | Zeaxanthin
相关库: Antioxidant Compound Library | Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Orally Active Compound Library | RO5 Drug-like Natural Product Library | Natural Product Library | Bioactive Compound Library
N,N-二甲基硫脲 T40615信息由TargetMol中国为您提供,如您想了解更多关于N,N-二甲基硫脲 T40615报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途