化合物BQR695 T4220
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 1513879-21-4 | ¥2,890.00 | 询底价 |
1 mL | 1513879-21-4 | ¥728.00 | 询底价 |
5 mg | 1513879-21-4 | ¥663.00 | 询底价 |
25 mg | 1513879-21-4 | ¥1,990.00 | 询底价 |
1 mg | 1513879-21-4 | ¥281.00 | 询底价 |
100 mg | 1513879-21-4 | ¥4,330.00 | 询底价 |
10 mg | 1513879-21-4 | ¥913.00 | 询底价 |
500 mg | 1513879-21-4 | ¥9,360.00 | 询底价 |
Product Introduction
Bioactivity
英文名: BQR-695
描述: BQR-695 (NVP-BQR695) 是一种磷脂酰肌醇 4-激酶抑制剂,对于人类和疟原虫 PI4KIIIβ 的 IC50值分别为 80 和 3.5 nM。
体外活性: BQR695 shows no evidence of toxicity against mature red blood cells (RBCs), induces a schizont-stage arrest indistinguishable from that observed in imidazopyrazine-treated parasites and exhibits cross-resistance with the imidazopyrazine-resistant lines. Treatment with 0.5 μM of either KAI407 or BQR695 causes GFP-PHOsh2 to redistribute to the parasite plasma membrane, consistent with depletion of intracellular PI4P upon inhibition of PfPI4K function.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (141.89 mM)
关键字: PI4K | PI4 kinases | Parasite | NVP-BQR-695 | BQR 695 | BQR-695 | Inhibitor | inhibit | Phosphatidylinositol 4 kinases | NVP-BQR 695
相关产品: Apitolisib | CAL-130 Hydrochloride | PI3kδ inhibitor 1 | PI3Kδ-IN-13 | PI-828 | PI3K-IN-10 | ARUK2001607 | PI3Kδ-IN-15 | Apilimod | Sprengerinin C
相关库: Anti-Aging Compound Library | PI3K-AKT-mTOR Compound Library | HIF-1 Signaling Pathway Compound Library | Angiogenesis related Compound Library | Neuronal Differentiation Compound Library | Inhibitor Library | Kinase Inhibitor Library | Anti-Parasitic Compound Library | Reprogramming Compound Library | Glycolysis Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途