化合物Succinobucol T4287
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 216167-82-7 | ¥493.00 | 询底价 |
10 mg | 216167-82-7 | ¥828.00 | 询底价 |
50 mg | 216167-82-7 | ¥2,820.00 | 询底价 |
1 mL | 216167-82-7 | ¥675.00 | 询底价 |
100 mg | 216167-82-7 | ¥4,250.00 | 询底价 |
500 mg | 216167-82-7 | ¥9,180.00 | 询底价 |
2 mg | 216167-82-7 | ¥297.00 | 询底价 |
25 mg | 216167-82-7 | ¥1,660.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Succinobucol
描述: Succinobucol (Probucol monosuccinate) 是酚类抗氧化剂,具有抗炎、抗血小板聚集活性。
细胞实验: In the metastatic 4T1 breast cancer cells, Succinobucol, SCB and the PCD polymer (equivalent concentration to SCB) are respectively added to each well with SCB concentrations ranging from 4 ng/mL to 40 μg/mL.
动物实验: Mice, injected 4T1-luc cells, are treated with Succinobucol (40 mg/kg) by tail injection every three days.
体外活性: In rabbit whole blood, Succinobucol (10, 50, 100 μM) causes a dose-dependent reduction in collagen-induced platelet aggregation. Succinobucol (10, 100 μM) significantly lowers the relaxation to X/XO.
体内活性: 在肺转移性乳腺癌小鼠中,通过尾部注射给予Succinobucol(40 mg/kg)显著降低了平均转移结节数。而在大鼠中,通过静脉注射Succinobucol(50、100、150 mg/kg)对心率或MAP均无显著影响。
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 45 mg/mL (72.94 mM)
关键字: Inhibitor | inhibit | Probucol Monosuccinate | AGI1067 | Reactive Oxygen Species | Succinobucol | Probucol | AGI 1067
相关产品: Girinimbine | (-)-Fenchone | Parishin C | Adrenochrome | Artemitin | Rhombifoline | Chrysin-7-O-glucuronide | Ethyl Vanillate | Oxypeucedanin hydrate | Gossypetin
相关库: Drug Repurposing Compound Library | Oxidation-Reduction Compound Library | Anti-Cancer Drug Library | Anti-Metabolism Disease Compound Library | Anti-Ovarian Cancer Compound Library | Human Metabolite Library | Anti-Cancer Clinical Compound Library | Anti-Diabetic Compound Library | Metabolism Compound Library | NO PAINS Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途