化合物MOZ-IN-3 T4362

Product Introduction
Bioactivity


英文名: WM-8014

描述: WM-8014 (MOZ-IN-3) 是一种 MOZ，属于组蛋白乙酰转移酶的抑制剂，IC50值为 55 nM。

激酶实验: Reactions are set up with Acetyl coenzyme A (AcCoA)(0.4 μM), N-terminal histone H4 peptide (sequence SGRGKGGKGLGKGGAKRHRKV-GGK-biotin)(50 nM), MOZ enzyme(10 nM), and an acetyl-lysine specific antibody (final dilution 1: 10000).

体外活性: MOZ-IN-3is an inhibitor of MOZ（IC50=55 nM）. MOZ-IN-3 causes cell senescence（IC50=1.6 μM） and suppresses the proliferation（IC50=551 nM）.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 45 mg/mL (117.06 mM)


关键字: HAT | inhibit | Inhibitor | HATs | WM 8014 | WM-8014 | Histone Acetyltransferase | WM8014

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相关库: Anti-Hypertension Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Inhibitor Library | Epigenetics Compound Library | Stem Cell Differentiation Compound Library | Anti-Cardiovascular Disease Compound Library | NO PAINS Compound Library | Histone Modification Compound Library | Bioactive Compound Library

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