芸苔宁 T4373

Product Introduction
Bioactivity


英文名: Brassinin

描述: Brassinin (BSN) 是一种从 B. campestris 中分离出来的植物抗毒素，具有抗癌、化学预防、抗增殖和抗真菌活性。

体外活性: In lung cancer cells, brassinin inhibits constitutive and IL-6-inducible STAT3 signaling through modulation of PIAS-3 and SOCS-3.It appears that brassinin induces apoptosis in PC-3 prostate cancer cells via the suppression of PI3K/Akt/mTOR/S6K1 signaling.

体内活性: Brassinin attenuates tumor growth in a xenograft lung cancer mouse model through modulation of E3 SUMO-protein ligase 3 (PIAS-3) and suppressor of cytokine signaling-3 (SOCS-3).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (232.71 mM)


关键字: Brassinine | inhibit | Inhibitor | Brassinin

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相关库: Anti-Tumor Natural Product Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Traditional Chinese Medicine Monomer Library | Anti-Fungal Compound Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Anti-Infection Compound Library | Anti-infective Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途