化合物B02 T4656
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 1290541-46-6 | ¥253.00 | 询底价 |
50 mg | 1290541-46-6 | ¥2,570.00 | 询底价 |
100 mg | 1290541-46-6 | ¥3,870.00 | 询底价 |
5 mg | 1290541-46-6 | ¥638.00 | 询底价 |
25 mg | 1290541-46-6 | ¥1,580.00 | 询底价 |
10 mg | 1290541-46-6 | ¥913.00 | 询底价 |
2 mg | 1290541-46-6 | ¥363.00 | 询底价 |
1 mL | 1290541-46-6 | ¥656.00 | 询底价 |
Product Introduction
Bioactivity
英文名: RAD51 Inhibitor B02
描述: RAD51 Inhibitor B02 (B02) 是一种人 RAD51的抑制剂,IC50值为27.4 μM。
体外活性: RAD51 Inhibitor B02 specifically inhibits human RAD51 (IC50=27.4 μM), but not its E. coli homologue RecA (IC50>250 μM).The combination of B02 with cisplatin has the strongest killing effect on the human breast cancer cells MDA-MB-231.
体内活性: B02 significantly enhances the therapeutic effect of cisplatin on tumor cells in vivo. B02 is tolerated by mice at doses up to 50 mg/kg without obvious body weight loss. No inhibition of tumor growth is observed on mice solely treated by B02; whereas mice treated with 4 mg/kg cisplatin show a 33% inhibition of tumor growth. Finally, mice treated with 50 mg/kg B02 and 4 mg/kg cisplatin shows a 66% inhibition of tumor growth[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 33.9 mg/mL(100 mM)
关键字: RAD51 Inhibitor B02 | B 02 | Apoptosis | RAD-51 Inhibitor B02 | RAD51 | Inhibitor | B-02 | inhibit
相关产品: Ziyuglycoside II | Methyl 3,4-dihydroxybenzoate | Decitabine | Neferine | Sodium dichloroacetate | Isoalantolactone | 2-Hydroxychalcone | Dauricine | PYR-41 | STM2457
相关库: Anti-Aging Compound Library | Cell Cycle Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | DNA Damage & Repair Compound Library | Apoptosis Compound Library | Target-Focused Phenotypic Screening Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途