短叶老鹳草素A T4672
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 16503-32-5 | ¥12,700.00 | 询底价 |
5 mg | 16503-32-5 | ¥2,970.00 | 询底价 |
50 mg | 16503-32-5 | ¥9,460.00 | 询底价 |
1 mL | 16503-32-5 | ¥3,270.00 | 询底价 |
500 mg | 16503-32-5 | ¥25,500.00 | 询底价 |
1 mg | 16503-32-5 | ¥785.00 | 询底价 |
10 mg | 16503-32-5 | ¥4,390.00 | 询底价 |
25 mg | 16503-32-5 | ¥6,870.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Brevilin A
描述: Brevilin A 是从Centipeda minima 中分离的倍半萜内酯,具有抗癌活性。它通过线粒体途径和 PI3K/AKT/mTOR 失活诱导结肠腺癌细胞 CT26 的凋亡和自噬。它是一种选择性JAK-STAT 信号通路抑制剂,通过减弱 JAK 信号和 阻塞 STAT3 信号起作用。
体外活性: In vitro activity against Giardia intestinalis was used for bioassay-guided fractionation of crude extracts from C. minima.?The sesquiterpene lactone, Brevilin A was isolated and found to have antigiardial activity (IC50 = 16.1 μM) and was similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM).?
存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 100 mg/mL (288.67 mM)
关键字: Brevilin A | Autophagy | Janus kinase | inhibit | Apoptosis | STAT | JAK | Inhibitor
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相关库: Anti-Tumor Natural Product Library | HIF-1 Signaling Pathway Compound Library | Mitochondria-Targeted Compound Library | Inhibitor Library | Kinase Inhibitor Library | Anti-Cancer Active Compound Library | Traditional Chinese Medicine Monomer Library | NO PAINS Compound Library | Anti-Infection Compound Library | Natural Product Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途