二羟基富马酸水合物 T4931

Product Introduction
Bioactivity


英文名: Dihydroxyfumaric acid hydrate

描述: Dihydroxyfumaric acid hydrate 是内源性代谢产物的一种。

体内活性: Corynoxine promotes the formation of autophagosomes in the fat bodies of Drosophila. By inducing autophagy, Corynoxine promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. Corynoxine induces autophagy through the Akt/mTOR pathway as evidenced by the reduction in the levels of phospho-Akt, phospho-mTOR and phospho-p70 S6 Kinase [1]. Corynoxine significantly decreased locomotor activity after oral administration to mice [2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (331.16 mM)


关键字: Dihydroxyfumaric acid | Inhibitor | Endogenous Metabolite | Dihydroxyfumaric acid hydrate | inhibit | Dihydroxyfumaric acid Hydrate

相关产品: Indole-3-carboxaldehyde | (±) Anabasine | Glycogen, Mussel | Butylparaben | Erythrodiol | D-Arabinose | L-Methionine sulfoxide | Glutathione oxidized | Cholesteryl sulfate sodium | D-Panthenol

相关库: Human Endogenous Metabolite Library | Covalent Natural Product Library | Human Metabolite Library | Human Endogenous Metabolite Compound Library Plus | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Covalent Inhibitor Library | Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途