四氢黄连碱 T4S2063

Product Introduction
Bioactivity


英文名: Tetrahydrocoptisine

描述: Tetrahydrocoptisine (STYLOPINE) 具有抑制炎症的有效作用。它通过抑制 NF-κB 信号通路对 LPS 诱导的 ALI 具有保护作用，这可能涉及抑制肺部炎症过程。它具有胃保护活性，归因于减少 NO 产生和调节促炎细胞因子，抑制中性粒细胞积累和 NF-κB 表达。它是一种活性抗炎成分，通过下调 NF-κB 活化、磷酸化 ERK1/2 和磷酸化-p38MAPK 信号通路抑制 TNF-α、IL-6 和 NO 的产生。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc. : Soluble
DMSO : 4.17 mg/mL (12.89 mM)


关键字: Tetrahydrocoptisine

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相关库: Anti-Aging Compound Library | Anti-Prostate Cancer Compound Library | Anti-Breast Cancer Compound Library | NF-κB Signaling Compound Library | Bioactive Compounds Library Max | Antidepressant Compound Library | Inhibitor Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Traditional Chinese Medicine Monomer Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途