香叶醇 T5665
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
500 mg | 106-24-1 | ¥997.00 | 询底价 |
100 mg | 106-24-1 | ¥418.00 | 询底价 |
1 mL | 106-24-1 | ¥230.00 | 询底价 |
50 mg | 106-24-1 | ¥298.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Geraniol
描述: Geraniol 对糖尿病引起的心脏功能障碍起保护作用,抑制氧化应激。
动物实验: Diabetes was induced in rats by a single streptozotocin injection. In the treated group,geraniol (150mg/kg/day) was administered orally starting from the 15th day after induction of diabetes, and ending after 7 weeks; diabetic control rats were given vehicle for the same period. At the end of the study, cardiac contractility was assessed by using a Millar microtip catheter in anesthetised rats, and cardiac conductivity determined by a surface ECG. Serum levels of glucose, cholesterol, triglyceride and adiponectin as well as urine 8-isoprostane were determined
体内活性: Geraniol prevented any increase in QTc and T-peak-T-end intervals, and markers of LV ischemia and arrhythmogenesis, seen in diabetic animals. Geraniol suppressed the exaggerated oxidative stress as evidenced by preventing the increase in 8-isoprotane. In diabetic heart tissue, geraniol prevented the inhibition in catalase activity but did not affect the heart SOD. Geraniol partially reduced hyperglycemia, prevented the hypercholesterolemia, but did not affect the serum level of adiponectin in diabetic animals.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 27.5 mg/mL (178.28 mM)
关键字: inhibit | Endogenous Metabolite | Inhibitor | Fungal | Geraniol
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相关库: Tobacco Monomer Library | Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Ferroptosis Compound Library | Traditional Chinese Medicine Monomer Library | Miao medicine Compound Library | Antiparasitic Natural Product Library | Tibetan medicine Compound Library | Traditional Mongolian Medicine Compound Library | NO PAINS Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途