三乙酰基白藜芦醇 T5668
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 42206-94-0 | ¥150.00 | 询底价 |
20 mg | 42206-94-0 | ¥110.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Triacetylresveratrol
描述: Triacetylresveratrol (Acetyl-trans-resveratrol) 是 Resveratrol 的乙酰化类似物,可降低 STAT3和 NF-κB 磷酸化,具有抗癌作用。
细胞实验: Apoptosis was determined by using apoptosis detection kit according to the manufacturers instructions.?Briefly, cells were treated with the indicated dosage of Acetyl-trans-resveratrol?for 48 h. The untreated and?treated cells were washed with PBS buffer and gently suspended in Annexin V binding buffer and incubated with Annexin V-FITC (20 μg/mL) and PI (20 μg/mL) for 15 minutes in the dark.?Flow cytometry analysis was performed using Cellquest software.
体外活性: Acetyl-trans-resveratrol inhibited cell viability, and induced apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner[1].
体内活性: Acetyl-trans-resveratrol significantly inhibited intracranial tumor growth and prolonged survival in these mouse models[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (141.1 mM)
关键字: Resveratrol | NF-κB | Triacetylresveratrol | inhibit | STAT | Anticancer | PANC-1 | Nuclear factor-kappaB | BxPC-3 | STAT3 | Nuclear factor-κB | Inhibitor
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途