高良姜素-3-甲醚 T5707

Product Introduction
Bioactivity


英文名: 3-O-Methylgalangin

描述: 3-O-Methylgalangin (GALANGIN-3-METHYLETHER) 是一种来源于高良姜根茎的天然黄酮，具有抗菌活性，抑制胰腺脂肪酶。

细胞实验: L. amazonensis amastigotes were maintained and cultured axenically .Washed parasites were resuspended in RPMI-1640 medium supplemented with 4% fetal calf serum, pH 5.0, and incubated at 33 C for 18 h with crude extracts (1 mg/mL) or isolated compounds(GALANGIN-3-METHYLETHER) (0.014, 0.084, 0.5, and 1.0 mg/mL) dissolved in dimethyl sulfoxide (DMSO)/RPMI-1640 (1:99).?The amastigote viability was assessed colorimetrically by the reduction of a tetrazolium salt (MTT) as.?Absorbances were expressed as percentages relative to untreated controls.?Amphotericin B (0.02 mg/mL) was used as the positive control and DMSO/RPMI-1640 (1:99) as negative control.?The bioassays were carried out in triplicate.

体外活性: GALANGIN-3-METHYLETHER markedly reduced the viability of Leishmania amastigotes.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 25 mg/mL (87.95 mM)


关键字: Galangin 3-methyl ether | Inhibitor | inhibit | Bacterial | 3-O-Methylgalangin | 3 O Methylgalangin | 3OMethylgalangin

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相关库: Polyphenolic Natural Product Library | Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Anti-Bacterial Compound Library | Anti-Infection Compound Library | Bioactive Compound Library | Anti-infective Natural Product Library

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