牛防风素 T5758
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 483-66-9 | ¥1,880.00 | 询底价 |
1 mL | 483-66-9 | ¥1,720.00 | 询底价 |
25 mg | 483-66-9 | ¥4,670.00 | 询底价 |
1 mg | 483-66-9 | ¥768.00 | 询底价 |
100 mg | 483-66-9 | ¥8,980.00 | 询底价 |
10 mg | 483-66-9 | ¥2,820.00 | 询底价 |
50 mg | 483-66-9 | ¥6,660.00 | 询底价 |
2 mg | 483-66-9 | ¥1,130.00 | 询底价 |
Product Introduction
Bioactivity
英文名: sphondin
描述: Sphondin 具有抗惊厥、抗炎和抗增殖活性,对 IL-1beta 诱导的 A549 细胞中 COX-2 蛋白水平和 PGE(2) 释放的增加具有抑制作用。
体外活性: Sphondin inhibits IL-1beta-induced PGE(2) release in A549 cells;?this inhibition is mediated by suppressing of COX-2 expression, rather than by inhibiting COX-2 enzyme activity.?The inhibitory mechanism of sphondin on IL-1beta-induced COX-2 expression may be, at least in part, through suppression of NF-kappaB activity. Sphondin may have the therapeutic potential as an anti-inflammatory drug on airway inflammation[1].
体内活性: Sphondin, showed anti-proliferative activity and caused G2/M arrest at concentrations of 0.05-15.0 Μm[2].
存储条件: keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 30 mg/mL (138.77 mM)
关键字: COX | airway | anti-inflammatory | epithelial | Cyclooxygenase | pulmonary | inflammation | inhibit | PGE2 | A549 | Inhibitor | COX-2 | sphondin
相关产品: Tolmetin | Moringin | Stylopine hydrochloride | α-Humulene | Tilmacoxib | Gaultherin | Phenylbutazone | Ginkgetin | Coniferaldehyde | Ketorolac tromethamine salt
相关库: Anti-Tumor Natural Product Library | Anti-Aging Compound Library | Anti-Prostate Cancer Compound Library | Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library | Anti-Cancer Compound Library | Membrane Protein-targeted Compound Library | GPCR Compound Library | Inhibitor Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途