化合物CK-869 T5860

Product Introduction
Bioactivity


英文名: CK-869

描述: CK-869 是一种肌动蛋白相关蛋白 2/3 复合体抑制剂，其 IC50值为 7 μM。

细胞实验: Cells were treated in suspension with different concentrations of the compounds, allowed to adhere to the surface of a tissue culture dish for one hour, washed and the number of adherent cells counted and presented as a fraction of untreated cells (10X lens, 10 fields/condition).?For cell spreading assays, cells were treated with CK-869 in suspension, plated on coverslips coated with 5 μg/ml fibronectin for imaging[1].

体外活性: CK-869 inhibits comet tail formation by L. monocytogenes with an IC50 value of 7 μM.It also impairs cell adhesion and cell spreading in MCF10A human breast epithelial cells[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 75 mg/mL (190.22 mM)


关键字: Arp2/3 Complex | inhibit | Inhibitor | CK869 | Actin-related protein 2/3 complex | CK 869 | CK-869

相关产品: Griseofulvin | T807 | PE859 | Epothilone A | SB-216 | AZ82 | ARN25068 | Jasplakinolide | KHS101 hydrochloride | Nocodazole

相关库: Anti-Aging Compound Library | Microtubule-Targeted Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Cytoskeletal Signaling Pathway Compound Library | Anti-Cardiovascular Disease Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途