氯虫苯甲酰胺 T60127
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 500008-45-7 | ¥318.00 | 询底价 |
10 mg | 500008-45-7 | ¥289.00 | 询底价 |
50 mg | 500008-45-7 | ¥755.00 | 询底价 |
100 mg | 500008-45-7 | ¥1,080.00 | 询底价 |
25 mg | 500008-45-7 | ¥493.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Chlorantraniliprole
描述: Chlorantraniliprole (Rynaxypyr) 是一种杀虫剂,能够有效地、选择性地激活鱼尼丁受体 (ryanodine receptor),对黑腹果蝇和烟芽夜蛾的 ryanodine 受体 EC50 值分别为 40 nM 和 50 nM,对其选择性是对小鼠骨骼肌 2C12 细胞 ryanodine 受体 (EC50,14 μM) 的 300 多倍。
体外活性: Chlorantraniliprole potently and selectively activates insect ryanodine receptor. Chlorantraniliprole actions by release of intracellular Ca2+ stores mediated by the ryanodine receptor. Chlorantraniliprole is ∼300-fold less potent against ryanodine receptor (RyRs) in the mouse myoblast cell line, C2C12 (EC50, 14 μM), than in insect RyRs from Drosophila melanogaster and H. virescens (EC50, 40 nM, 50 nM), and shows little selectivity at the rat cell line RyR2 (EC50, >100 μM)[1].
体内活性: Chlorantraniliprole has low acute mammalian toxicity with an acute oral LD50 of >5000 mg/kg in rats, and little to no toxicity in 90-day studies, at dosing as high as 1500 mg/kg/day[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 56.7mg/mL (117.4mM)
关键字: Chlorantraniliprole
相关库: Bioactive Compounds Library Max | Bioactive Compound Library
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